PGT (Preimplantation Genetic Testing)

    Advanced Embryo Genetic Testing for More Informed IVF Treatment

    Preimplantation Genetic Testing (PGT) is an advanced laboratory procedure performed during IVF to evaluate embryos before embryo transfer. Depending on the clinical indication, PGT can help identify certain chromosomal abnormalities or specific inherited genetic conditions, allowing fertility specialists to make more informed decisions when selecting embryos for transfer.

    At Nova Plus, we work with carefully selected fertility clinics that offer advanced genetic testing through accredited laboratories, following internationally recognized medical standards.

    What is PGT?

    PGT is performed during an IVF cycle after embryos have developed to the blastocyst stage.

    A small number of cells are carefully biopsied from the embryo and analyzed in a specialized genetics laboratory. Following the biopsy, embryos are typically cryopreserved while the genetic analysis is completed. Once the results are available, your fertility specialist will discuss the findings and recommend the most appropriate embryo(s) for transfer based on your individual treatment plan.

    Types of Preimplantation Genetic Testing

    PGT-A

    Preimplantation Genetic Testing for Aneuploidy (PGT-A) evaluates embryos for chromosomal abnormalities, including missing or extra chromosomes.

    PGT-A may be recommended for:

    • Women of advanced maternal age
    • Recurrent pregnancy loss
    • Repeated IVF implantation failure
    • Severe male factor infertility
    • Previous embryos with chromosomal abnormalities
    • Patients seeking additional embryo assessment

    The goal of PGT-A is to help identify embryos with the normal number of chromosomes, which may improve embryo selection during IVF treatment.

    PGT-M

    Preimplantation Genetic Testing for Monogenic Disorders (PGT-M) is used when one or both intended parents are known carriers of specific inherited genetic conditions.

    Depending on the family's medical history, PGT-M may help reduce the risk of passing certain inherited diseases to future children.

    Examples include:

    • Cystic Fibrosis
    • Thalassemia
    • Tay-Sachs Disease
    • Fragile X Syndrome
    • Sickle Cell Disease
    • Other inherited disorders where clinically appropriate

    Testing is individualized according to each family's genetic history and specialist recommendations.

    PGT-SR

    PGT-SR is recommended for patients with structural chromosomal rearrangements, such as balanced translocations or inversions.

    The purpose is to identify embryos with balanced chromosome structures before transfer.

    Family Balancing Consultation

    Some intended parents ask whether embryo testing can provide information related to embryo sex.

    Nova Plus follows the laws and regulations of the country where treatment is provided. Depending on the jurisdiction and applicable legal framework, information available through genetic testing and the options that may be discussed can vary.

    Our team is happy to explain the regulations that apply to your treatment destination during a private consultation.

    Why Choose Nova Plus?

    • Access to advanced PGT technologies
    • Experienced fertility specialists
    • Accredited genetic laboratories
    • Personalized treatment planning
    • Trusted IVF clinic partners
    • International patient coordination
    • Dedicated multilingual coordinator
    • Transparent medical guidance

    Frequently Asked Questions

    Does PGT improve IVF success rates?

    PGT does not guarantee pregnancy. However, in appropriate patients, it may help fertility specialists select embryos with normal chromosomal findings, which can support treatment planning.

    Is embryo biopsy safe?

    When performed by experienced embryologists using established laboratory protocols, embryo biopsy is generally considered a well-established procedure with a low risk of affecting embryo development.

    How long does PGT take?

    Genetic analysis is typically completed within one to three weeks, depending on the laboratory and testing performed.

    Is PGT recommended for everyone?

    Not necessarily. PGT is recommended based on individual medical history, age, reproductive history, and specialist recommendations.

    Can PGT identify every genetic condition?

    No. Different PGT tests evaluate different types of genetic abnormalities. Your fertility specialist or genetic counselor will explain which tests are appropriate for your specific circumstances.

    Written by:Nova Plus Editorial TeamLast reviewed:

    Medical & Legal References

    The statements on this page are supported by the official sources below. Primary legal documents are linked in their original publication and may open in another language.

    1. Good practice recommendations for preimplantation genetic testing (PGT)European Society of Human Reproduction and Embryology (ESHRE) · Europe
    2. Pre-implantation genetic testing for aneuploidy (PGT-A)Human Fertilisation & Embryology Authority (HFEA) · United Kingdom
    3. Pre-implantation genetic testing for monogenic disorders (PGT-M) and PGT-SRHuman Fertilisation & Embryology Authority (HFEA) · United Kingdom
    4. Law of the Republic of Armenia on Human Reproductive Health and Reproductive Rights — Articles 11, 12, 13, 15ARLIS — Legal Information System of Armenia · Armenia · 2002

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